pentobarbital raises toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/keep an eye on. CYP3A4 inducers may perhaps increase the metabolism of ifosfamide to its Energetic alkylating metabolites. observe Closely (1)pentobarbital will lessen the extent or impact of fentanyl transmucosal by influencing hepati